The Oldest Drug Store
On the corner of Orange and Cordova streets, the Oldest Drug Store stands on ground that old town maps mark as a Native American village — a Tolomato mission settlement later absorbed into the Spanish colonial city, its people displaced. By the late 1880s the Speissegger family ran a working druggist's shop here, its shelves lined with glass bottles of tonics, opium, and cocaine remedies; today the building survives as a remedy shop and museum near the ancient cemetery. The legend holds that an unfriendly spirit, bitter over how the land's first inhabitants were forced out, never left the spot. Visitors and shopkeepers have told of remedy jars found scattered across the floor in the night, and of a dim apparition glimpsed after dark among the antique shelves. Paranormal investigators report cold spots, photographic anomalies, and recorded voices in the cramped old rooms.
📍 31 Orange Street, St. Augustine, FL 32084, St. Augustine, FL · Get directions